01Mn
Naturally derived
manganese SOD
Derived from naturally occurring Bacillus amyloliquefaciens, this SOD uses manganese as its cofactor.
NATURALLY DERIVEDNATURE. FERMENTATION. SCIENCE.
Rooted in nature.
Explored through
science.
Meet SODyZYM, a naturally derived manganese SOD.
Produced through fermentation. Investigated in human studies.
SUPEROXIDE DISMUTASENature-inspired brand imagery
SCROLL TO EXPLORE 01 Naturally derived Mn-SOD02 Microbial fermentation03 Human study evidence
01 / ABOUT SODyZYM
Get to know
an antioxidant enzyme.
SOD.
Your antioxidant defense system
includes an enzyme called SOD.
SOD stands for Superoxide Dismutase. This enzyme converts superoxide, a type of reactive oxygen species. Other enzymes, including catalase and glutathione peroxidase, then continue the antioxidant process.
SODyZYM is a manganese SOD enzyme ingredient made by fermenting naturally derived Bacillus microorganisms and purifying the resulting enzyme.
SODyZYM, a fermentation-produced enzymeMn-SOD · Superoxide DismutaseAn SOD enzyme ingredient brand by HLB Genex
This describes the general biological role of SOD and does not imply that supplementation produces the same effects.
02 / OUR DIFFERENCE
Three reasons
to know your ingredient.
Explore its origins, how it is produced,
and the research behind it.
Naturally derived
02F
Produced by fermentation.
Refined by purification.
We use our proprietary microbial strain to produce SOD through fermentation, then purify it to create the enzyme ingredient.
CRAFTED BY FERMENTATION03H
Investigated
in human studies
Bacillus-derived SOD, the ingredient behind SODyZYM, has been investigated in human studies with results published in scientific journals.
HUMAN STUDIESNaturally derived strain→Fermentation→Purification→SODyZYM
OUR FERMENTATION PROCESS
Our proprietary strain.
Our fermentation expertise.
HLB Genex produces SOD through fermentation using a microbial strain developed in-house. From cultivation and fermentation to purification, this process creates the SODyZYM enzyme ingredient.
03 / HUMAN EVIDENCE
A closer look
at the evidence.
Understand the findings
alongside the study conditions.
Randomized · Double-blind · Placebo-controlledAntioxidant responses
Read the publication
Antioxidant responses
to exercise-induced oxidative stress.
Healthy adults received Bacillus-derived SOD or a placebo. Researchers compared antioxidant markers before and after an aerobic exercise challenge.
80peopleParticipants randomized
8weeksSupplementation period
500IU/dayMn-SOD dose used in the study
WHAT THE STUDY OBSERVED
After a single dose
Researchers observed lower exercise-induced reactive oxygen species (ROS) levels and increased SOD activity in red blood cells.
With repeated supplementation
Changes in antioxidant defenses were reported, including catalase activity and reduced glutathione (GSH) levels.
These results were observed under specific exercise-challenge conditions. They do not guarantee the same response or everyday health benefits for everyone.
Randomized · Double-blind · Active-controlledExploring antioxidant markers
Read the publication
Exploring antioxidant markers
in women undergoing IVF.
This study compared GF101, a Bacillus-derived SOD, with coenzyme Q10 (CoQ10) in women undergoing in vitro fertilization (IVF).
86peopleParticipants enrolled
12weeksStudy duration
CoQ10Active comparator
HOW TO READ THE RESULTS
Changes within the GF101 group
Serum catalase increased significantly from baseline after 12 weeks in the GF101 group (p=0.004).
Comparison between groups
Between-group differences in changes in serum SOD and catalase were not statistically significant.
This study involved a specific patient population. It does not establish fertility benefits for the general public or an infertility treatment effect.
Nam Y. et al. Free Radical Biology and Medicine 224 (2024), 484–493.
How do human and preclinical studies differ?
Human studies involve people, while preclinical studies use cells, animals or other models. Animal findings cannot be directly interpreted as benefits in humans. This page focuses on human studies. The formulations, doses and participant characteristics in these studies may differ from those of finished consumer products.
04 / GET IN TOUCH
Want to know more
about SODyZYM?
Contact HLB Genex with your questions
about SODyZYM and its ingredients.